Motif ID: STAT5{A,B}.p2

Z-value: 0.833


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Achr17_+_404395640.195.8e-03Click!
STAT5Bchr17_-_404283110.111.1e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_35168558 12.363 NM_001012320
NM_018443
 ZNF302

zinc finger protein 302

chr11_+_73357222 10.572 NM_001130033
NM_021200
 PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr19_-_37019169 9.635 NM_001012756
NM_001166036
NM_001166037
NM_001166038
 ZNF260



zinc finger protein 260



chr19_+_44576266 9.110 NM_001037813
 ZNF284
zinc finger protein 284
chr5_+_178286913 8.594 NM_058230
 ZNF354B
zinc finger protein 354B
chr7_+_142829169 7.791 NM_002652
 PIP
prolactin-induced protein
chr20_-_43280359 7.717 NM_000022
 ADA
adenosine deaminase
chr20_+_34556528 7.402 NM_001207076
NM_080834
 C20orf152

chromosome 20 open reading frame 152

chr19_+_58095507 7.230 NM_001010879
 ZIK1
zinc finger protein interacting with K protein 1 homolog (mouse)
chr20_-_43280249 7.050 ADA
adenosine deaminase
chr1_+_54519259 6.763 NM_153035
 TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr19_+_37407230 6.713 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
 ZNF568





zinc finger protein 568





chr19_+_44598479 6.623 NM_013398
 ZNF224
zinc finger protein 224
chr15_+_66874506 6.008


chr19_-_58427934 5.920 NM_152475
 ZNF417
zinc finger protein 417
chr19_-_58326280 5.917 NM_024762
 ZNF552
zinc finger protein 552
chr19_+_35225095 5.397 ZNF181
zinc finger protein 181
chrY_+_2709596 5.336 NM_001008
 RPS4Y1
ribosomal protein S4, Y-linked 1
chr19_+_39882018 5.123 MED29
mediator complex subunit 29
chr8_-_56685869 5.037 NM_152417
 TMEM68
transmembrane protein 68

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.61 1.12e-12 GO:0006355 regulation of transcription, DNA-dependent
2.51 8.88e-12 GO:0051252 regulation of RNA metabolic process
2.48 2.90e-12 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.44 3.98e-12 GO:0010556 regulation of macromolecule biosynthetic process
2.31 1.98e-10 GO:0010468 regulation of gene expression
2.30 1.81e-02 GO:0032774 RNA biosynthetic process
2.27 1.45e-10 GO:0009889 regulation of biosynthetic process
2.27 2.33e-10 GO:0031326 regulation of cellular biosynthetic process
2.21 1.97e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.20 1.18e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.98 1.96e-08 GO:0060255 regulation of macromolecule metabolic process
1.88 2.90e-07 GO:0031323 regulation of cellular metabolic process
1.84 1.92e-06 GO:0080090 regulation of primary metabolic process
1.80 7.42e-07 GO:0019222 regulation of metabolic process
1.38 1.98e-04 GO:0065007 biological regulation
1.38 2.82e-03 GO:0050794 regulation of cellular process
1.37 2.66e-03 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.56 1.94e-06 GO:0005634 nucleus
1.27 3.42e-04 GO:0043229 intracellular organelle
1.27 3.95e-04 GO:0043226 organelle
1.27 2.90e-03 GO:0043231 intracellular membrane-bounded organelle
1.27 3.12e-03 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.59 1.04e-12 GO:0008270 zinc ion binding
2.53 7.52e-14 GO:0003677 DNA binding
2.43 2.94e-12 GO:0046914 transition metal ion binding
1.93 2.07e-08 GO:0003676 nucleic acid binding
1.77 1.78e-07 GO:0043169 cation binding
1.77 2.04e-07 GO:0043167 ion binding
1.77 2.21e-07 GO:0046872 metal ion binding